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Mycotoxins & Mold

How to Know If Mold Is Making You Sick: Testing Beyond the Obvious

By Dr. Michelle Hirsch, DACM · October 4, 2026 · 10 min read

How to Know If Mold Is Making You Sick: Testing Beyond the Obvious

Have you been struggling with fatigue, brain fog, poor sleep, digestive issues, hormonal symptoms, or a collection of health concerns that never seem to fully resolve? Have you tried changing your diet, taking supplements, improving your sleep, and following the recommendations you've been given — yet you still don't feel like yourself?

It may be time to look beyond the obvious and consider your environment.

Mold and mycotoxin exposure are areas I believe deserve much more attention when we're trying to understand complex, chronic health concerns. In my practice, I've seen how important it can be to consider environmental factors when someone has been working hard to improve their health but continues to struggle. If this resonates, our mycotoxins & mold care goes deeper into how we approach it.

The challenge is that mold-related issues aren't always easy to recognize. The source of exposure may be hidden, symptoms can affect multiple systems throughout the body, and conventional evaluations may not explore the connection between a person's environment and their health.

Understanding what to look for — and how to investigate it — can be an important first step toward finding answers.

Mold and mycotoxins: what's the difference?

Mold is a type of fungus that grows when moisture and suitable nutrients are present. It may be visible on a wall or ceiling, but it can also grow behind drywall, beneath flooring, around windows, inside HVAC systems, or in other areas where moisture has accumulated.

Mycotoxins are compounds produced by certain types of fungi under particular conditions. Not all molds produce mycotoxins, and not every mold problem creates the same exposure. Understanding this distinction matters because looking for visible mold is not necessarily the same as investigating potential mycotoxin exposure.

One important detail is that mycotoxins themselves have no distinctive smell. A musty odor may signal moisture or microbial growth, but the absence of an odor does not mean a building is free of hidden mold.

Our modern indoor environments also deserve a closer look. Buildings are often constructed or renovated to be tightly sealed for energy efficiency. When moisture intrusion, condensation, plumbing leaks, or inadequate ventilation are also present, conditions can develop that allow mold to grow and persist.

A home can look beautiful, feel clean, and appear well maintained while still having a moisture problem hidden inside a wall, beneath a floor, or in another part of the building.

This is why I encourage people to look beyond what they can see and smell. The history of a building, its moisture patterns, and the health patterns of the people living or working inside it may offer important clues.

Signs mold could be part of your health picture

Mold exposure is commonly associated with allergic and respiratory symptoms, including congestion, sneezing, irritated eyes, coughing, wheezing, and worsening asthma. Some people notice that they feel better when they leave a particular building and worse when they return.

For others, the picture can be much more complicated.

In clinical practice, I pay attention when someone experiences several persistent symptoms that seem difficult to connect. These may include:

  • Ongoing fatigue or feeling depleted despite adequate rest
  • Brain fog, difficulty concentrating, or memory concerns
  • Headaches or a general sense of feeling unwell
  • Poor sleep or difficulty feeling rested
  • Digestive symptoms or changes in bowel habits
  • Hormonal or metabolic concerns
  • Increased sensitivity to their surroundings
  • Symptoms that seem to worsen at home, at work, or in another frequently occupied building

These symptoms can have many contributing factors, so the goal is not to assume that mold explains everything. Rather, it is to recognize when environmental exposure deserves to be investigated alongside the other pieces of a person's health history.

I also look at how a potential exposure may intersect with the body's interconnected systems.

Mitochondria help produce the energy our cells need to function. Hormone signaling influences metabolism, mood, and many other processes. The stress-response system plays a role in our ability to adapt, while healthy sleep supports recovery and regulation. The gut lining and other barrier systems help maintain the body's internal balance, and the gut microbiome contributes to digestion and broader physiological functions.

Certain mycotoxins are known to affect biological processes under particular conditions, and researchers continue to investigate their effects. In patients with complex symptoms, I consider whether environmental exposures may be one factor contributing to a larger pattern of dysfunction.

The important point is to look at the whole person rather than treating every symptom as an isolated problem.

Why mold-related problems can be overlooked

One reason mold can be missed is that its potential effects may look like many other health concerns. A patient may see one provider for fatigue, another for digestive symptoms, and another for hormonal issues. Each symptom may be addressed separately, while a possible shared environmental factor remains unexplored.

Another challenge is that exposure is not always obvious. Mold can grow in places we rarely inspect, and a past water leak may have left behind a problem that continues long after the visible damage has been repaired.

I believe we need to become more comfortable asking questions about the environments in which people live and work, particularly when they have persistent symptoms that have not responded as expected to other interventions.

Individual responses can also vary considerably. The amount and duration of exposure, the characteristics of the building, a person's underlying health, and individual differences in biological processes may all play a role in how someone responds.

Two people can live in the same home and have very different experiences. One may notice relatively little, while another may struggle significantly. This is one reason I don't believe we can evaluate a person's situation based on the building alone or assume that everyone will respond in the same way.

Genetics, overall health, nutrition, sleep, stress, and the body's capacity to process and eliminate compounds are all areas worth considering as part of a broader assessment. No single factor tells the entire story.

For someone who has been dismissed, told that their symptoms are simply stress, or left without a clear explanation, exploring environmental exposure may open up a new avenue of investigation.

Testing beyond the obvious

When mold is a concern, I think about two related questions: what is happening in the environment, and what might be happening in the person?

Neither question should be considered in isolation. A thoughtful investigation brings together the building history, symptom patterns, relevant testing, and the person's overall clinical picture.

1. Investigating the home

Start by considering the history of the building. Has there been flooding, a roof leak, plumbing damage, condensation, recurring dampness, or a musty area that never seems to resolve? Are there rooms where symptoms seem to worsen? Has the building undergone renovations that may have concealed previous water damage?

A qualified building professional can help investigate moisture and potential mold growth in areas that are not readily visible.

One environmental test I often consider is ERMI (Environmental Relative Moldiness Index). ERMI analyzes dust for DNA from selected mold species and can provide information about the mold profile in a home. It is one tool that may help guide further investigation, particularly when the concern involves hidden mold.

Like any environmental test, ERMI needs to be interpreted in context. It does not independently establish whether a building is making someone sick, and a result should not replace a careful assessment of moisture, building conditions, and the people occupying the space.

The goal is to identify potential sources of exposure and understand what needs to be addressed — not simply to collect a report.

2. Patient testing: looking for clues inside the body

Patient testing is another part of the process. Depending on the person and the clinical questions involved, practitioners may consider urine or blood testing as part of a broader evaluation.

Urine mycotoxin testing is used by some practitioners to investigate the presence of certain mycotoxins or their metabolites in urine. The results need to be considered alongside the patient's history, possible dietary sources, environmental findings, symptoms, and other relevant information.

Some practitioners also use glutathione as part of their approach to detoxification support and mycotoxin evaluation. In my clinical approach, I may consider this when deciding how to investigate a patient's situation. It is important to understand that protocols intended to mobilize stored compounds or change their excretion are still evolving, and their interpretation requires care.

Blood testing may also have a role depending on the concern being evaluated. For example, conventional allergy testing can help investigate suspected mold allergy, while other blood tests may help assess symptoms or identify contributing conditions.

There is no single test that answers every question. The value comes from selecting appropriate tests, understanding what they measure, and considering how the findings fit together.

3. Looking at the gut and the bigger picture

I also pay attention to the gut microbiome and other findings that may provide additional clues.

For example, if a stool test shows a striking reduction in beneficial commensal bacteria, I may ask more questions about the patient's history, medications, diet, gastrointestinal health, and environmental exposures. Some fungi produce compounds with antimicrobial properties, so this type of finding may prompt a broader investigation.

A disrupted microbiome is not specific to mold, but it can be one piece of a larger clinical picture.

This is where experience and careful interpretation matter. A test result means more when we understand the person behind it: their symptoms, the timeline of their illness, the places where they spend time, their medical history, and what has or has not helped so far.

Rather than looking for one perfect test, I want to build a clearer picture of what may be contributing to the person's health challenges.

What happens if mold is part of the problem?

Identifying a potential exposure is only the beginning. The next step is to determine what needs to change.

If there is a moisture problem or active mold growth, addressing the source is essential. Cleaning the visible area without correcting the underlying moisture may allow the problem to return. Depending on the location and extent of the damage, professional remediation may be needed.

In some cases, repairs are manageable. In others, the situation is more complicated and expensive. People may need to make difficult decisions about remediation, temporary relocation, or whether moving is ultimately the best option.

These decisions can be emotionally and financially exhausting, especially when someone is already dealing with health challenges. Having a clearer understanding of the building conditions can help people make informed decisions about their next steps.

On the health side, the approach needs to be individualized. This may involve supporting sleep and nutrition, addressing digestive or hormonal concerns, evaluating other contributing conditions, and working with a qualified practitioner on an appropriate plan.

Recovery is not always quick. When someone has been struggling for a long time, there may be multiple issues to address, and meaningful progress can take patience. Environmental changes and health interventions may need to happen together.

I encourage patients to think in terms of a thoughtful, step-by-step process rather than expecting one supplement, one test, or one treatment to resolve everything overnight.

When to ask for help

Consider looking more closely at mold and environmental exposure if you have persistent symptoms, a history of water damage in your home or workplace, recurring moisture problems, or a pattern in which you feel different in certain environments.

You do not need to have visible mold on your walls to ask questions. And you do not need to have every symptom on a checklist for an environmental investigation to be worthwhile.

A healthcare practitioner familiar with complex chronic illness can help review your history, evaluate possible contributing factors, and determine what testing may be appropriate. A qualified building professional can help assess moisture and potential mold problems in the environment.

If you have significant or worsening symptoms, it is also important to seek appropriate medical evaluation rather than assuming that mold is the only possible cause.

The bottom line

Mold and mycotoxin exposure deserve a place in the conversation about chronic health concerns, particularly when someone has been struggling without meaningful answers.

The signs are not always obvious. The source may be hidden, symptoms may involve multiple systems, and different people may respond differently to similar environments. Looking beyond visible mold and considering the broader clinical picture can help uncover questions that might otherwise go unasked.

In my practice, I want patients to understand that their symptoms deserve attention and that exploring the environment may be an important part of finding answers.

If you have been doing everything you know to do for your health and still feel that something is being missed, it may be time to look beyond the obvious.

Sometimes, understanding what is happening around you is an important step toward understanding what is happening within you.

If this sounds like your experience, a discovery call is the simplest place to start. It's free, it's 15 minutes, and it's a conversation about what's going on — not a commitment.

This article is for general education and isn't a substitute for individualized medical advice. If you suspect mold may be affecting your health, working with a qualified healthcare provider and a professional mold inspector can help you understand your exposure and how to address it.

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